Two step calibration method for ozone low-cost sensor: Field experiences with the UrbanSense DCUs.

Urban air pollution is a global concern impairing citizens' health, thus monitoring is a pressing need for city managers. City-wide networks for air pollution monitoring based on low-cost sensors are promising to provide real-time data with detail and scale never before possible. However, they still present limitations preventing their ubiquitous use. Thus, this study aimed to perform a post-deployment validation and calibration based on two step methods for ozone low-cost sensor of a city-wide network for air pollution and meteorology monitoring using low-cost sensors focusing on the main challenges. Four of the 23 data collection units (DCUs) of the UrbanSense network installed in Porto city (Portugal) with low-cost sensors for particulate matter (PM), carbon monoxide (CO), ozone (O3), and meteorological variables (temperature, relative humidity, luminosity, precipitation, and wind speed and direction) were evaluated. This study identified post-deployment challenges related to their validation and calibration. The preliminary validation showed that PM, CO and precipitation sensors recorded only unreliable data, and other sensors (wind speed and direction) very few data. A multi-step calibration strategy was implemented: inter-DCU calibration (1st step, for O3, temperature and relative humidity) and calibration with a reference-grade instrument (2nd step, for O3). In the 1st step, multivariate linear regression (MLR) resulted in models with better performance than non-linear models such as artificial neural networks (errors almost zero and R2 > 0.80). In the 2nd step, the calibration models using non-linear machine learning boosting algorithms, namely Stochastic Gradient Boosting Regressor (both with the default and post-tuning hyper-parameters), performed better than artificial neural networks and linear regression approaches. The calibrated O3 data resulted in a marginal improvement from the raw data, with error values close to zero, with low predictability (R2 ∼ 0.32). The lessons learned with the present study evidenced the need to redesign the calibration strategy. Thus, a novel multi-step calibration strategy is proposed, based on two steps (pre and post-deployment calibration). When performed cyclically and continuously, this strategy reduces the need for reference instruments, while probably minimising data drifts over time. More experimental campaigns are needed to collect more data and further improve calibration models.

A novel dry active electrode for EEG recording.

The design and testing of a "dry" active electrode for electroencephalographic recording is described. A comparative study between the EEG signals recorded in human volunteers simultaneously with the classical Ag-AgCl and "dry" active electrodes was carried out and the reported preliminary results are consistent with a better performance of these devices over the conventional Ag-AgCl electrodes.

[Computerized electrocardiography system of Porto. I -- General description and experience with its use]. / O sistema do Porto de electrocardiografia computorizado. I--Descrição geral e experiência de Utilização.

After a brief review of computer assisted ECG interpretation techniques, a microcomputer-based system for off-line ECG (Frank) analysis and interpretation developed at the University of Porto is presented. The program is menu-structured and includes report correction and editing facilities. Clinical data can be stored along with the ECG in the individual patient file. More than 500 characteristics are extracted from the ECG signal by the measurement section of the program. The diagnostic section uses Boolean-tree logic. The diagnostic threshold values and interpretation statements are kept in an independent file and can be changed at any moment by the user. Taking the cardiologist using the same logic and criteria as reference standard, an evaluation of the diagnostic efficiency of the system was performed in 509 reports from pediatric and adult patients: 7% of the reports needed corrections and 113 (3.7%) out of 3070 diagnostic statements produced had to be changed. Output options include the clinical data, more or less extensive listings of the wave measurements, X, Y and Z and polar plots and the 12-lead (derived) ECG, besides the interpretation report itself.

Classification of breast tissue by electrical impedance spectroscopy.

Electrical impedance spectroscopy is a minimally invasive technique that has clear advantages for living tissue characterisation owing to its low cost and ease of use. The present paper describes how this technique can be applied to breast tissue classification and breast cancer detection. Statistical analysis is used to derive a set of rules based on features extracted from the graphical representation of electrical impedance spectra. These rules are used hierarchically to discriminate several classes of breast tissue. Results of statistical classification obtained from a data set of 106 cases representing six classes of excised breast tissue show an overall classification efficiency of approximately 92% with carcinoma discrimination > 86%.

Incidência do vírus influenza A e B na populaçäo de Maceió-AL, Brasil / Incidence of influenza A and B viruses among the population of Maceió-AL, Brazil

Vírus respiratórios säo responsáveis por uma grande percentagem das doenças na populaçäo humana. Um estudo soro-epidemiológico foi feito para determinar a prevalência de anticorpos para as cepas do subtipo A: A/ Taiwan/1/86 (H1N1), A/Shangdong/9/93 (H3N2), A/Shanghai/11/87 (H3N2) e A/Wuhan/359/95 (H3N2) foi 189, 223,230 e 103 amostras, respectivamente. E para o subtipo B: B/Panamá/45/20, B/Guangdong/8/93 e B/Beijing/184/93 foi 191, 126 e 103 amostras, respectivamente. Os soros foram obtidos no período de 1996/1997, de pacientes internos e externos do Hospital Universitário (HU) da Universidade Federal de Alagoas de diferentes faixas etárias e de ambos os sexos. A técnica utilizada para pesquisar anticorpos específicos foi a de Inibiçäo da Hemaglutinaçäo (HI). A prevalência de anticorpos para A/Taiwan/1/86 (H1N1), A/Shaigdong/9/93 (H3N2), A/Shangai/11/87 (H3N2) e A/Wuhan/359/95 (H3N2) foi 94 porcento, 93 porcento, 81 porcento e 78 porcento respectivamente e o B/Panamá/45/20, B/Guangdong/8/93 e B/Beijing/184/93 foi 52 porcento, 23 porcento e 53 porcento respectivamente. A presença de marcadores sorológicos do Vírus Influenza A e B em nossa populaçäo evidenciada pela primeira vez e mostrou ser em índices elevados, indicando uma ampla disseminaçäo desses subtipos

Automatic classifiers for the interpretation of electrocardiograms.

The morphological diagnosis of ECGs is a pattern recognition procedure. The way the clinician does this is not clearly elucidated. Nevertheless, several models aimed at achieving identical results by automatic means are empleyed. While in the doctor's case this is not exactly so, the computer task for ECG interpretation comprises two distinct and sequential phases: feature extraction and classification. A set of signal measurements containing information for the characterization of the waveform is first obtained. These waveform descriptors are then used to allocate the ECG to one or more diagnostic classes in the classification phase. The classifier can embody rules-of-thumb used by the clinician to decide between conflicting ECG diagnosis and formal or fuzzy logic as a reasoning tool (heuristic classifiers). On the other hand, it can use complex and even abstract signal features as waveform descriptors and different discriminant function models for class allocation (statistical classifiers). More recently, artificial neural network techniques have also been used for signal classification. The authors review feature selection techniques and classification strategies, problems and methods of performance evaluation and results obtained by different classification approaches. A brief discussion of the relative merits of the two main types of ECG classifiers, logical and statistical, is included.

Classification of foetal heart rate sequences based on fractal features.

Visual inspection of foetal heart rate (FHR) sequences is an important means of foetal well-being evaluation. The application of fractal features for classifying physiologically relevant FHR sequence patterns is reported. The use of fractal features is motivated by the difficulties exhibited by traditional classification schemes to discriminate some classes of FHR sequence and by the recognition that this type of signal exhibits features on different scales of observation, just as fractal signals do. To characterise the signals by fractal features, two approaches are taken. The first modes the FHR sequences as temporal fractals. The second uses techniques from the chaos-theory field and aims to model the attractor based on FHR sequences. The fractal features determined by both approaches are used to design a Bayesian classification scheme. Classification results for three classes are presented; they are quite satisfactory and illustrate the importance of this type of methodology.

[Automated analysis of cardiotocographic signals]. / Análise automática de sinais cardiotocográficos.

Cardiotocographic signals, used as a perinatal diagnostic tool, comprise fetal heart beat signals (FHR), uterine contractions (UC) and fetal movements (FM). Visual inspection of these three signals is limited, subjective, time consuming and with low reproducibility. The present paper illustrates an application of signal processing techniques to the automatic analysis of cardiotocographic signals, allowing to overcome visual inspection limitations. Porto system of cardiotocograms automatic analysis acquires the signals from a conventional cardiotocograph. The signals are stored and processed by a personal computer. System software allows the user to perform several operations such as signal acquisition, signal storage and retrieval from files, signal analysis and display. Signal analysis is preceded by various signal conditioning operations (filtering, spike removal, etc.) and consists in the estimation of several parameters with diagnostic value: FHR baseline; FHR accelerations and decelerations; uterine contractions; long and short term FHR variability. The system prototype is working on a routine basis at the Obstetrics Department of S. João Hospital (main Oporto Hospital) and is being evaluated using a large data set. A preliminary evaluation performed by 3 experts on a 50 cases set, yielded an agreement rate with computer measurements of 98% for the baseline, 72% to 82% for accelerations and decelerations and 76% for the uterine contractions.

The Porto system for automated cardiotocographic signal analysis.

Cardiotocography (CTG) lacks reliability and reproducibility and these problems are believed to be overcome by computer analysis. In this article we describe a system developed for routine clinical automated CTG analysis based on a low cost personal computer. Presently the system has processed 70 ten minute tracings. Fetal heart rate baseline, acceleration--deceleration detection, and long term variability estimation were performed in a satisfactory way.

Interpretation of short ECGs with a personal computer: the Porto program.

A computer program for ECG analysis and interpretation developed at the University of Porto, Portugal is presented. The program runs on a microcomputer and employs the three-lead Frank VCG. The signals are sampled at 250 Hz with 8-bit precision during 5.5 s. Details on signal conditioning and wave recognition and measurement techniques are given. The diagnostic part of the program uses decision-tree logic. The decision rules are mainly derived from the Washington Code. The diagnostic accuracy of four classes (normal, left and right ventricular hypertrophies and myocardial infarction), evaluated in a sample of 1,075 pediatric and adult patients and classified by ECG-independent means was 76%. The program is currently being evaluated on the CSE database.

Frontal-plane QRS axis revisited: accuracy of current approximations and reappraisal of their merit in the diagnosis of right ventricular hypertrophy.

The frontal-plane mean QRS vector orientation (AQRSxy)--the so-called electrical axis--is an ECG feature commonly used for the diagnosis of right ventricular hypertrophy and is correctly measured by calculating the areas subtended by QRS deflections in two different leads. To overcome the drawbacks of doing this by hand, two alleged approximations of AQRSxy have become popular and are in current use: one is based on the measurement of QRS component wave peak amplitudes and the other on the estimation of the half-area vector of the frontal plane loop. The values obtained with the correct and the two more practical methods are compared and their diagnostic efficiency is assessed by means of a procedure for ECG criteria optimization based on the receiver operating characteristics (ROC) curve analyzed in terms of information theory. The authors conclude that the two more popular methods for AQRSxy determination provide similar values that, although correlated with the true measure of the parameter are statistically different from it. On the other hand, the diagnostic efficiency of AQRSxy alone, regardless of the method by which it is computed, is only as good as, if not bettered by, other much more easily measurable frontal-plane parameters (ie, left to rightward forces amplitude ratio in adults and rightward forces amplitude in pediatric patients).

A new ECG classifier based on linear prediction techniques.

A longstanding tradition in automatic ECG classification has been the use of conventional features (amplitudes, duration, etc.) as waveform descriptors for pattern discrimination purposes. This paper presents an alternative approach in statistical ECG classification. It is based on the use of linear prediction coefficients, a sort of "abstract" features which, as waveform descriptors, enjoy the desirable property of whole-signal dependency, being rather insensitive to high-frequency noise. Experimental results obtained on 400 ECGs distributed by four clinical groups according to clinicopathological data (normal, myocardial infarction, right and left hypertrophies) show interesting potentialities of this new method, namely a classification error for equal class prevalences (30%) significantly lower than by using conventional features. Classification and cluster separability results are presented and discussed as well as the viability of the new method in a clinical environment.